The State Institute of Applied Chemistry (GIPKh), part of the Rostec State Corporation, has developed a technology for the production of raw materials for anesthetic agent sevoflurane. The substance has been produced in Russia before. This is reported by the GIPKh press center.
The drug is used for general and local anesthesia in surgery and dentistry, as well as to provide care to victims of serious accidents. The technology will enable pharmaceutical companies to produce the drug in Russia and overcome the dependence on imported supplies, the report says.
Sevoflurane belongs to halogenated agents for inhalation anesthesia and is often administered in a mixture with nitrous oxide and oxygen. This anesthetic agent is one of those with the fastest action.
The drugs of the group to which sevoflurane belongs are highly efficient, manageable, and do not have a negative effect on internal organs. All that guarantees their safe use.
“Our technology allows us to obtain the anesthetic in the form of a technical substance for further production of the finished dosage form at the licensed pharmaceutical enterprises. We are ready to provide the pharmaceutical industry with at least 50 tons per year of raw materials for the production of sevoflurane. It is now critically important for the country to minimize the dependence on external supplies of medicines, and our development brings us closer to this goal,” Elena Kozlova, the General Director of AO RRC Applied Chemistry (GIPKh), commented.