Russian scientists have created a vaccine for livestock and poultry that provides simultaneous protection against two dangerous infections — salmonellosis and colibacillosis. Currently, vaccination against each of these diseases is provided separately. The new vaccine was developed by researchers from Belgorod State National University, the Stavropol Biopharmaceutical Plant, and the Institute of Biochemistry and Physiology of Microorganisms of the Russian Academy of Sciences, according to the press service of the Ministry of Education and Science.
The developers have obtained a unique strain of Salmonella enteritidis R-6 ecp-schomo, a genetically modified version of the bacterium that causes Salmonella enteritidis. Cells of this new strain actively produce specific proteins that stimulate antibody production and help establish a stable immunity against two serious bacterial diseases. Based on this strain, a vaccine manufacturing technology was developed.
“A universal vaccine significantly increases the effectiveness of prevention, reduces production costs, and simplifies veterinary procedures to protect poultry and livestock, which is of great importance for the agricultural economy,” the report notes.
The two-component vaccine has undergone experimental and clinical trials, and its registration with the Ministry of Agriculture is currently being prepared. The development has been granted priority for patenting in Russia, and the Salmonella enteritidis R-6 ecp-schomo strain has been deposited in the All-Russian Collection of Microorganisms.
Earlier, the All-Russian Scientific Research Institute for Animal Protection released a comprehensive vaccine for cats, Carnifel PCHR, which is called the “first domestic drug providing protection against infectious diseases and rabies.”
