Researchers at Novosibirsk State Technical University (NSTU) have developed a biopolymer gel for delivering medications containing beneficial bacteria to the intestines of animals, the university’s press service reported.
Preparations containing both probiotics and prebiotics have proven effective as treatments for animals. Their drawback is that they do not reach the intestines in full volume: some of the beneficial bacteria die in the stomach. NSTU scientists have found a way to solve this problem by creating a special gel.
“Our development is aimed at protecting bacteria and their metabolites from the high acidity of the stomach. To achieve this, we are proposing a polymer-based gel, similar to the one we previously created to preserve brewing yeast. It not only allows synbiotics to reach the intestines but also acts as a substrate—a nutrient medium for beneficial bacteria,” said project leader Victoria Bets.
The expert also noted that the effectiveness of the biopolymer system has been proven in laboratory conditions: experiments on germ-free mice showed that thanks to the polymer gel, the number of bacteria in the animals’ intestines increased significantly.
Victoria Bets emphasized that during the gel studies, researchers achieved controlled delivery of probiotic components to the targeted sections of the intestines. According to her, this has proven the 100% effectiveness of the development.
NSTU scientists also plan to create a comprehensive preparation containing bacteria and auxiliary substances, and test it on various types of farm animals.
